The Johns Hopkins Hospital
600 North Wolfe Street
Phipps 446
Baltimore, MD 21287
Division of Cerebrovascular Neurology
The Johns Hopkins University School of Medicine
Publications
Original Research
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Kiehl EL, Parker A, Matar RM, Gottbrecht MF, Johansen MC, Adams MP, Griffiths LA, et al. "C‐GRApH: A Validated Scoring System for Early Stratification of Neurologic Outcome After Out‐of‐Hospital Cardiac Arrest Treated With Targeted Temperature Management." Journal of the American Heart Association 6, no. 5 (2017): e003821. Adjudicated all neurological outcomes, edited final version
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Johansen MC, Shah AM, Lirette ST, Griswold M, Mosley TH, Solomon SD, Gottesman RF. Associations of Echocardiography Markers and Vascular Brain Lesions: The ARIC Study. J Am Heart Assoc. 2018 Dec 18;7(24):e008992.
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Johansen MC, Lin M, Nazarian S, Gottesman RF. Associations of echocardiographic features with stroke in those without atrial fibrillation. Neurology. 2019 Feb 26;92(9):e924-e932.
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Johansen MC, Gottesman RF, Urrutia VC. Cerebral venous thrombosis: Associations between disease severity and cardiac markers. Neurology: Clinical Practice. 2019 May 17:10-212.
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Johansen MC, Mosley TH, Knopman DS, Wong DF, Wagenknecht LE, Shah AM, Solomon SD, Gottesman RF. The Associations between Left Ventricular structure, function and Cerebral Amyloid: The ARIC-PET study. Stroke. 2019 Dec;50(12):3622-3624.
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Al Rifai M, Blaha MB, Ahmed A, Almosoudi F, Johansen MC, Qureshi W, Sakr S, Virani SS, Brawner CA, Ehrman JK, Keteyian SJ, Al-Mallah MH. Cardiorespiratory Fitness and Incident Stroke Types: The FIT (Henry Ford ExercIse Testing) Project. 2020 Mayo Clinic Proceedings, 95 (7), pp. 1379-1389. Provided neurology expertise regarding stroke etiology, edited draft and revisions.
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Yahya T, Blaha M, Johansen MC. Stroke in the Young Adult: Current Trends, Opportunities for Prevention and Pathways Forward. American Journal of Preventive Cardiology, Volume 3, 2020, 100085. Manuscript revision and subject matter expertise.
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Johansen MC, Mosley TH, Knopman DS, Wong DF, Ndumele C, Shah AM, Solomon SD, Gottesman RF. The Associations between Atrial Cardiopathy and Cerebral Amyloid: The ARIC-PET study. The Journal of the American Heart Association. 2020 Dec 15;9(24):e018399.
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Johansen MC, Doria de Vasconcellos H, Nazarian S, Lima JAC, Gottesman RF. The Investigation of Left Atrial Structure and Stroke Etiology: The I-LASER Study. The Journal of the American Heart Association. 2021 Jan 19;10(2):e018766.
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Khan SU, Khan MZ, Khan MU, Mamas AM, Rashid M, Blankstein R, Virani SS, Johansen MC, Blaha MJ, Cainzos-Achirica Miguel, Vahidy FS, Nasir K. Clinical and Economic Burden of Stroke Among Young, Midlife and Older Adults in the United States, 2002 – 2017. Mayo Clin Proc Innov Qual Outcomes. 2021 Apr 8;5(2):431-441. Subject matter expertise, conceptual design, manuscript revisions.
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Obisedan OH, Osei AD, Berman D, Dardari ZA, Uddin SM, Dzaye O, Orimoloye OA, Budoff MJ, Miedema MD, Rumberger J, Mirbolouk M, Boakye E, Johansen MC, Rozanski A, Shaw L, Nasir K, Blaha MJ. Thoracic Aortic Calcification for the prediction of stroke mortality: The Coronary Artery Calcium Consortium. Am J Cardiol. 2021 Mar 2:S0002-9149(21)00213-7. Manuscript revisions.
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Ziai WC, Cho SM, Johansen MC, Ergin B, Bahouth MN. Transcranial Doppler in Acute COVID-19 Infection: Unexpected Associations. Stroke. 2021 Jul;52(7):2422-2426. Data collection, statistical analysis, manuscript revisions.
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Johansen MC, Gottesman RF, Kral BG, Vaidya D, Yanek LR, Becker LC, Becker DM, Nyquist P. Association of Coronary Artery Atherosclerosis with Brain White Matter Hyperintensity. Stroke. Stroke. 2021 Aug;52(8):2594-2600.
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Williams NL, Suarez A, Negoita S, Hillis AE, Gottesman RF, Johansen MC. Cardiac Structure and Function is Associated with Hemispatial Neglect Severity. Front Neurol. 2021 May 6;12:666257.
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Johansen MC, Nyquist P, Sullivan KJ, Fornage M, Gottesman RF, Becker DM. Cerebral small-vessel disease in individuals with a family history of coronary heart disease: The Atherosclerosis Risk in Communities Study. Neuroepidemiology. 2021;55(4):316-322.
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Yahya T, Jilani MH, Khan SU, Mszar R, Hassan SZ, Blaha MJ, Blankstein R, Virani SS, Johansen MC, Vahidy F, Cainzos-Achirica M, Nasir K. Stroke in young adults: Current trends, opportunities for prevention and pathways forward. Am J Prev Cardiol. 2020 Sep 9;3:100085. Manuscript revisions, subject matter expertise.
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Daneshvari NO, Johansen MC. Associations between cerebral magnetic resonance imaging infarct volume and acute ischemic stroke etiology. PLoS One. 2021 Aug 23;16(8):e0256458.
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Selvaraj S, Claggett B, Johansen MC, Cunningham JW, Gottesman RF, Yu B, Boerwinkle E, Mosley TH, Shah AM, Soloman SD. APOE Polymorphism, Cardiac Remodeling, and Heart Failure in the ARIC Study. Journal of Cardiac Failure. J Card Fail. 2021 Dec 26:S1071-9164. Manuscript revision.
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Johansen MC, Wang W, Zhang MJ, Alonso A, Wong DF, Gottesman RF, Chen LY. Associations Between Atrial Arrhythmias and Brain Amyloid Deposition: The ARIC-PET Study. Journal of Alzheimer's Disease. 2022 Jan 4(Preprint):1-5.
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Koton S, Pike J, Johansen MC, Knopman DS, Lakshminarayan K, Mosley T, Patole S, Rosamond WD, Schneider ALC, Sharrett R, Wruck L, Coresh J, Gottesman RF. Ischemic Stroke Incidence, Severity, and Recurrence as Risk Factors for Dementia in the Atherosclerosis Risk in Communities (ARIC) Cohort Study. JAMA Neurology. 2022 Jan 24. Study conceptualization, collection of data, recruitment of other neurologists to work on the study, manuscript drafting, revisions and publication.
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Wang W, Zhang MJ, Inciardi RM, Norby FL, Johansen MC, Parikh R, Van’t Hof JR, Alonso A, Soliman EZ, Mosley TH, Gottesman RF, Shah AM, Solomon SD, Chen LY. Association of echocardiographic measures of left atrial function and size with incident dementia. JAMA. 2022 Mar 22;327(12):1138-1148. Study conceptualization, manuscript revisions and subject matter expertise.
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Hicks CW, Wang D, Schneider ALC, Johansen MC, Gottesman RF, Matsushita K, Coresh J, Windham BG, Selvin E. Associations of Peripheral Neuropathy Defined by Monofilament Insensitivity with Mild Cognitive Impairment and Dementia in Older Adults. Dement Geriatr Cogn Disord. 2022 Mar 28:1-9. Manuscript revisions and editing.
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Bianco F, De Caterina R, Chandra A, Aquila I, Clagett B, Johansen MC, Goncalves A, Norby F, Cogswell R, Soliman E, Gottesman RF, Mosley T, Alonso A, Shah A, Solomon S, Chen L. Left atrial remodeling and stroke in patients with sinus rhythm and normal ejection fraction: the ARIC-NCS Study. JAHA. 2022 May 3. Manuscript revisions and editing.
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Hannawi Y, Vaidya D, Yanek LR, Johansen MC, Kral BG, Becker LC, Becker DM, Nyquist PA. Association of Vascular Properties with the Brain White Matter Hyperintensities in Middle-Age Population. JAHA. 2022 Jun 7. Preliminary data collection and analysis from my previous work formed foundation for study, manuscript revisions.
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Johansen MC, Wang W, Zhang M, Knopman D, Ndumele C, Mosley T, Selvin E, Shah A, Solomon, S, Gottesman RF, Chen LY. The Risk of Dementia Associated with Atrial Cardiopathy: The Atherosclerosis Risk in Communities (ARIC) Study. JAHA. 2022 Aug 10:e025646.
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Koton S, Patole S, Carlson JM, Haight T, Johansen M, Schneider ALC, Pike JR, Gottesman RF, Coresh J. Methods for stroke severity assessment by chart review in the Atherosclerosis Risk in Communities Study. Sci Rep. 2022 Jul 19;12(1):12338. Manuscript revision, data collection, content development.
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Zhao D, Gootee E, Johansen MC. Atrial Cardiopathy is Associated with Cerebral Microbleeds in Ischemic Stroke Patients. Frontiers in Neurology. 2022 Sept 01; 13.
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Gootee E, Stein C, Walker A, Daneshvari N, Blaha M, Lima J, Gottesman F, Johansen MC. Normal left atrial diameter is associated with better performance on a cognitive screener among a cohort of ischemic stroke patients. Frontiers Neurology. 2022 November 24.
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Maheshwari A, Norby FL, Inciardi RM, Wang W, Zhang MJ, Soliman EZ, Alonso A, Johansen MC, Gottesman R, Solomon SD, Shah AM, Chen LY. Left Atrial Mechanical Dysfunction and the Risk of Ischemic Stroke in People Without Atrial Fibrillation or Stroke: The Atherosclerosis Risk in Communities (ARIC) Study. Annals of Internal Medicine. 2023 Jan 17. Content expert, abstract drafting, reviewing manuscript for content.
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Johansen MC, Ye W, Gross A, Gottesman RF, Han D, Whitney R, Briceno EM, Giordani BJ, Shore S, Elkind MSV, Manly JJ, Sacco RL, Fohner A, Griswold M, Psaty BM, Sidney S, Sussman J, Yaffe K, Moran AE, Heckbert S, Hughes TM, Galecki A, Levine DA. Association Between Acute Myocardial Infarction and Decline in Cognition: A Pooled Cohort Analysis of the ARIC, MESA, CARDIA, CHS, FOS and NOMAS studies. JAMA Neurology. Published online May 30, 2023.
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Reyes JL, Norby FL, Wang W, Parikh R, Oldenburg NC, Lutsey PL, Jack CR, Johansen M, Gottesman RF, Coresh J, Mosley T, Soliman EZ, Alonso A, Chen LY. Association of Abnormal P-Wave Parameters with Brain MRI Morphology: The Atherosclerosis Risk in Communities Neurocognitive Study (ARIC-NCS). Pacing and Clinical Electrophysiology. 2023 Mar 16. Manuscript revision, content expert.
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Liberman AL, Wang Z, Zhu Y, Hassoon A, Cho J, Austin M, Johansen MC, Lehman H, Newman-Toker, DE. Optimizing Measurement of Misdiagnosis-Related Harms using Symptom-Disease Pair Analysis of Diagnostic Error (SPADE): Comparison Groups. Diagnosis. 2023 Apr 5. Subject matter expert, critical review of the manuscript, editing of the manuscript.
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Zhang MJ, Ji Y, Wang W, Norby FL, Parikh R, Eaton AA, Inciardi RM, Alonso A, Soliman EZ, Mosley TH, Johansen MC, Gottesman RF, Shah AM, Solomon SD, Chen LY (2023). Association of Atrial Fibrillation with Stroke and Dementia Accounting for Left Atrial Function and Size. JACC Adv 2(2). Accepted May 6 2023. In press. Content expert, review of the manuscript, editing of the manuscript.
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Ehrman JK, Keteyian SJ, Johansen MC, Blaha MJ, Al-Mallah MH, Brawner CA. Improved cardiorespiratory fitness is associated with lower incident ischemic stroke risk: Henry Ford FIT project. J Stroke Cerebrovasc Dis. 2023 Jun 30. Drafting the manuscript and revising it critically for intellectual content.
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Johansen MC, Chen J, Schneider ALC, Carlson J, Haight T, Lakshminarayan K, Patole S, Gottesman RF, Coresh J, Koton S. The Association between Ischemic Stroke Subtype and Stroke Severity: The Atherosclerosis Risk in Communities Study. Neurology. 2023 Jul 6.
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Okine DN, Knopman DS, Mosley TH, Wong DF, Johansen MC, Walker KA, Jack Jr CR, Pike JR, Graff-Radford J, Gottesman RF. Cerebral Microbleed Patterns and Cortical Amyloid-β: The ARIC-PET Study. Stroke. Accepted Aug 1 2023. In press. Critical manuscript review for content and format, subject matter expert.
Case Reports
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Gailloud P, Deib G, Pearl MS, Khoshnoodi M, Johansen MC. Intersegmental artery dissection resulting in spinal infarction. Neurology: Clinical Practice. 2019 Oct 30. DOI: https://doi.org/10.1212/CPJ.0000000000000766.
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Evan, J, Akst, L, Johansen MC. Dysphagia, dysphonia and a deviated tongue: Diagnosing Collet-Sicard Syndrome. BMJ Case Reports. 2021 May 21;14(5):e243154.
Book chapter
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Hao Q, Johansen MC, Wityk R. Chapter 81 – Posterior Circulation: Large Artery Occlusive Disease and Embolism In: Caplan LR, Biller J, Leary MC, Lo EH, Thomas AJ, Yenari M, and Zhang JH, eds., Primer on Cerebrovascular Diseases, Second Edition, San Diego: Academic Press, 2017: pp-pp 392-397. Co-first author, collection of data, drafting of manuscript, editing and review of manuscript.
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Zhao D, Arthur, K, Naghani, IM, Johansen MC. Chapter 11-Maternal Stroke In: Contemporary Topics in Cardio-Obstetrics. Springer Nature. Accepted May 11, 2023. In Press.
Invited Review Articles
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Chapman SN, Mehndiratta P, Johansen MC, McMurry TL, Johnston KC, Southerland AM. Current perspectives on the use of intravenous recombinant tissue plasminogen activator (tPA) for treatment of acute ischemic stroke. Vascular health and risk management. 2014;10:75. Review and collection of the latest data, drafting of the review article, manuscript edits.
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Johansen MC, De Vasconcellos, HD, Gottesman, RF. “Understanding Atrial Cardiopathy: An Under-Recognized Contributor to Cardioembolic Stroke.” Curr Treat Options Neurol (2019) 21: 32.
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Johansen MC, Langton-Frost N & Gottesman RF. The Role of Cardiovascular Disease in Cognitive Impairment. Curr Geri Rep (2020).
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Arthur K, Fracica L, Johansen MC. Stroke treatment in the setting of Systemic Disease. Current Treatment Options in Neurology. Curr Treat Options Neurol 22, 44 (2020).
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Johansen MC, Gottesman, RF. Cerebrovascular Disease and Cognitive Outcome in Patients with Cardiac Disease. Semin Neurol. 2021 Apr 13.
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Johansen MC. The Future of Ischemic Stroke Diagnosis and a Review of Underrecognized Ischemic Stroke Etiologies. Neurotherapeutics. 2023 May 8.
Editorials
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Cole, JW, Johansen, MC.Risk of recurrent cervical artery dissection. Neurology Mar 2018, 10.1212/WNL.0000000000005322; DOI: 10.1212/WNL.0000000000005322
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Johansen MC, Sheth, KN. Is incident stroke associated with increased risk of major adverse cardiovascular events? Neurology. 2020 Mar 10. pii: 10.1212/WNL.0000000000009235. doi: 10.1212/WNL.0000000000009235.
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Gottesman, RF, Johansen, MC. Coronary revascularization and cognitive decline: The patient or the procedure? JAMA. 2021 May 18;325(19):1941-1942.
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Johansen MC, Blaha MJ. Coronary Artery Calcium: A Risk Factor for Brain Aging? Circ Cardiovasc Imaging. 2021 Jul;14(7):e013062.
Brief Reports and Expert Opinion
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Johansen MC, Geocadin RG and Kamel H. Embolic Stroke of Unknown Source Clinical Trials and Advances in Research. Ann Neurol. doi:10.1002/ana.25825
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Johansen MC, Jones-London M, Koroshetz W, Masliah E, Nath A, Whittemore V, McArthur JC. ANA Webinar: Clinical and Basic Research Resilience during COVID-19. Annals of Clinical and Translational Neurology: doi: 10.1002/acn3.51230.
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Johansen MC, Campbell BCV. ANA Investigates: Tenecteplase. Ann Neurol. 2021 May 2. doi: 10.1002/ana.26093.
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Johansen MC, Cereda CW, Heit JJ. ANA Investigates: Basilar Artery Stroke. Ann Neurol. 2022 Apr;91(4):441-442.
PUBLICATIONS OF JOHANSEN LAB MEMBERS
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Williams NL, Suarez A, Negoita S, Hillis A, Gottesman RF, Johansen MC. Cardiac Structure and Function is Associated with Hemispatial Neglect Severity. https://2020.myana.org/sites/default/files/docs/2020/final_ana_volume_88_issue_s25.pdf (October 2020)
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Kwon, R, Gottesman, RF, Johansen, MC. Pre-morbid Ischemic Stroke Functioning Impacts Stroke Recovery, Independent of Stroke Severity. (April 2021).
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Gootee, E, Stein, C, Walker, A, Daneshvari, N, Blaha, M, Lima, J, Gottesman, RF, Johansen, MC. Evaluating the Impact of Stroke Subtype on Cognitive Impairment in Ischemic Stroke Patients. (October 2021)